Source: http://www.thehollywoodgossip.com/2013/06/game-of-thrones-fans-react-to-latest-deaths-no-way/
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সোমবার, ৩ জুন, ২০১৩
Blog Curry | The First Steps On Your Self Help Journey
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Source: http://blogcurry.com/2013/06/the-first-steps-on-your-self-help-journey.html
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রবিবার, ২ জুন, ২০১৩
Therapy that heats and destroys bone tumors eases patients' pain
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Public release date: 2-Jun-2013[ | E-mail |
Share ] Contact: Danielle Servetnick
danielle.servetnick@jefferson.edu
215-955-2238
Thomas Jefferson University
(CHICAGO) Patients with cancer that has spread to their bones are often treated with radiation therapy to reduce pain. But if that treatment doesn't work, or can't be used again, a second, effective option now exists. Results of a clinical trial on the new therapy, presented by a researcher at Jefferson's Kimmel Cancer Center, is being presented at the annual meeting of the American Society of Clinical Oncology (ASCO).
Mark Hurwitz, MD, Director of Thermal Oncology for the Department of Radiation Oncology at Thomas Jefferson University and Hospital reported that the treatment, magnetic resonance image-guided focused ultrasound (MRIgFU) ablation therapy, significantly reduced pain in 67 percent of patients who received the treatment. The device, known as ExAblate, uses numerous small ultrasound beams designed to converge on a tumor within bone, heat it and destroy it.
"Pain is a common, often debilitating symptom of the spread of cancer to bones. We are pleased to now have a second therapy that can improve a patient's enjoyment of life," says Dr. Hurwitz, who led the clinical trial. A number of cancers spread to bones, and a substantial proportion of patients live for years with these metastases, which can have a profound impact on a patient's quality of life, he adds.
The findings of the trial led to approval of ExAblate last October by the U.S. Food and Drug Administration as second-line therapy for palliation of painful metastatic bone tumors. The first-line therapy is typically radiotherapy.
"The response to ExAblate was as good as radiotherapy, which was notable because it is very unusual to see a second-line treatment with a response rate that is as high as first-line therapy," Dr. Hurwitz says.
He added that use of ExAblate offers several advantages compared to other ablative therapies. "It is non-invasive and provides more detailed anatomic information so that we can visualize the complete beam path to make sure that critical structures such as vessels and nerves are not in the way," Dr. Hurwitz says. "We are also able to monitor the temperature in the tumor as well as in nearby normal tissues so that we do not inadvertently heat normal organs and tissues."
ExAblate has also been approved for treatment of uterine fibroids.
The study led by Dr. Hurwitz is a multicenter, randomized and placebo-controlled phase three clinical trial. The 142 patients enrolled could either not undergo, or had not responded to, radiation treatment.
Three months after ExAblate therapy, 67 percent of treated patients reported significant improvement in pain, compared to 21 percent in the placebo arm. They typically rated their pain as "much improved" or "very much improved," Dr. Hurwitz says. A quality of life assessment also measured significant improvement.
"The treatment is given just once, and a response occurs within days," he says. "There are a lot of patients who could potentially benefit from MR guided focused ultrasound."
###
The clinical trial was sponsored by Insightec Ltd., who developed ExAblate.
Thomas Jefferson University (TJU), the largest freestanding academic medical center in Philadelphia, is nationally renowned for medical and health sciences education and innovative research. Founded in 1824, TJU includes Jefferson Medical College (JMC), one of the largest private medical schools in the country and ranked among the nation's best medical schools by U.S. News & World Report, and the Jefferson Schools of Nursing, Pharmacy, Health Professions, Population Health and the Graduate School of Biomedical Sciences. Jefferson University Physicians is TJU's multi-specialty physician practice consisting of the full-time faculty of JMC. Thomas Jefferson University partners with its clinical affiliate, Thomas Jefferson University Hospitals.
[ | E-mail | Share ] ?
AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.
Public release date: 2-Jun-2013[ | E-mail |
Share ] Contact: Danielle Servetnick
danielle.servetnick@jefferson.edu
215-955-2238
Thomas Jefferson University
(CHICAGO) Patients with cancer that has spread to their bones are often treated with radiation therapy to reduce pain. But if that treatment doesn't work, or can't be used again, a second, effective option now exists. Results of a clinical trial on the new therapy, presented by a researcher at Jefferson's Kimmel Cancer Center, is being presented at the annual meeting of the American Society of Clinical Oncology (ASCO).
Mark Hurwitz, MD, Director of Thermal Oncology for the Department of Radiation Oncology at Thomas Jefferson University and Hospital reported that the treatment, magnetic resonance image-guided focused ultrasound (MRIgFU) ablation therapy, significantly reduced pain in 67 percent of patients who received the treatment. The device, known as ExAblate, uses numerous small ultrasound beams designed to converge on a tumor within bone, heat it and destroy it.
"Pain is a common, often debilitating symptom of the spread of cancer to bones. We are pleased to now have a second therapy that can improve a patient's enjoyment of life," says Dr. Hurwitz, who led the clinical trial. A number of cancers spread to bones, and a substantial proportion of patients live for years with these metastases, which can have a profound impact on a patient's quality of life, he adds.
The findings of the trial led to approval of ExAblate last October by the U.S. Food and Drug Administration as second-line therapy for palliation of painful metastatic bone tumors. The first-line therapy is typically radiotherapy.
"The response to ExAblate was as good as radiotherapy, which was notable because it is very unusual to see a second-line treatment with a response rate that is as high as first-line therapy," Dr. Hurwitz says.
He added that use of ExAblate offers several advantages compared to other ablative therapies. "It is non-invasive and provides more detailed anatomic information so that we can visualize the complete beam path to make sure that critical structures such as vessels and nerves are not in the way," Dr. Hurwitz says. "We are also able to monitor the temperature in the tumor as well as in nearby normal tissues so that we do not inadvertently heat normal organs and tissues."
ExAblate has also been approved for treatment of uterine fibroids.
The study led by Dr. Hurwitz is a multicenter, randomized and placebo-controlled phase three clinical trial. The 142 patients enrolled could either not undergo, or had not responded to, radiation treatment.
Three months after ExAblate therapy, 67 percent of treated patients reported significant improvement in pain, compared to 21 percent in the placebo arm. They typically rated their pain as "much improved" or "very much improved," Dr. Hurwitz says. A quality of life assessment also measured significant improvement.
"The treatment is given just once, and a response occurs within days," he says. "There are a lot of patients who could potentially benefit from MR guided focused ultrasound."
###
The clinical trial was sponsored by Insightec Ltd., who developed ExAblate.
Thomas Jefferson University (TJU), the largest freestanding academic medical center in Philadelphia, is nationally renowned for medical and health sciences education and innovative research. Founded in 1824, TJU includes Jefferson Medical College (JMC), one of the largest private medical schools in the country and ranked among the nation's best medical schools by U.S. News & World Report, and the Jefferson Schools of Nursing, Pharmacy, Health Professions, Population Health and the Graduate School of Biomedical Sciences. Jefferson University Physicians is TJU's multi-specialty physician practice consisting of the full-time faculty of JMC. Thomas Jefferson University partners with its clinical affiliate, Thomas Jefferson University Hospitals.
[ | E-mail | Share ] ?
AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.
Source: http://www.eurekalert.org/pub_releases/2013-06/tju-tth053113.php
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শনিবার, ১ জুন, ২০১৩
SUNY partners with Coursera for massively open online course experiment
Massive open online courses have the potential to alter how we teach and learn as a society, but unlike other methods that are steeped in centuries of trial and error, the MOOC concept remains experimental and unproven -- often criticized as better suited for edification than rigorous education. Like edX, Coursera is working to challenge that assumption, and today the online course provider announced partnerships with ten public university systems that'll integrate lessons from Coursera into the classroom. Most notably, The State University of New York is participating, which boasts 64 campuses and an enrollment of nearly half a million students. While its implementation remains up in the air, SUNY aims to introduce Coursera materials this fall and over the next few years as part of its Open SUNY initiative.
Like SUNY, all partner schools may adapt lessons from Coursera as they see fit, and professors will have the opportunity to develop online courses for Coursera. Most significantly, the pilot programs will give universities an opportunity to evaluate the effectiveness of Coursera material, which could go a long way toward legitimizing the MOOC concept. As another happy consequence, universities may choose to offer for-credit courses from Coursera to non-matriculated students. For a greater understanding of this grand experiment, just hit up the source links.
[Image credit: Dave Herholz / Flickr]
Filed under: Internet
Via: The Verge, InformationWeek
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Qatar joins other Gulf States in clamping down on online media ... - RT
The Gulf nation of Qatar is set to approve a range of new measures that aim to monitor online activity by its citizens, and could well lead to punishment for websites and users that breach the ?general order?.
The draft of the country?s new media laws has moved on to an advisory council for final approval, and has been expected at least for the past year.
In March, Hamad bin Abdulaziz Al Kuwari, Qatar?s Minister of Arts, Culture and Heritage, publicly stated that social media would be covered by the new media laws as ?it is the most important form of free expression in the present world.?
Now, as AP reports, Qatar will seek wide leeway that could see consequences for online items considered a threat to ?state security?, and it further outlaws news, video or online posts that violate the ?sanctity? of a person?s private life, regardless of whether it is slanderous.
The new measures seem to resemble those enacted in other Western-backed Gulf states such as Kuwait and Bahrain, which have sharply increased arrests linked to social media posts that insult or otherwise undermine rulers.
In Bahrain, the government has gone through great lengths to project a positive public perception, and has been intolerant of activism over media such as Twitter since it first began to experience a swell in demonstrations brought on by the Arab Spring.
Bloggers in Bahrain, as well as in Kuwait, have been subject to prosecution for comments deemed seditious or ?blasphemous? against the monarchies. In September of last year, for example, a high court in Bahrain sentenced prominent independent blogger and human rights activist Abduljalil Alsingace to life imprisonment on charges of ?plotting to topple? the country?s leadership.
According to the Committee to Protect Journalists, in 2012 Bahrain saw some of the worst conditions for journalists in the country since King Hamad bin Issa al-Khalifa assumed power in 1999. CPJ documented three journalists? deaths, dozens of detentions, deportations, and smear campaigns.
In the case of Qatar, Jamie Ingram, a Middle East analyst at IHS Global Insight, sees similarities between the country?s new online media regulations and those of other Gulf nations.
?The law in Qatar and the UAE are strikingly similar ? the UAE enacted this legislation in November of last year and Qatar?s now following suit. They?re very concerned by the potential for unrest and there have been restrictions on freedom of speech and this law is simply acknowledging modern technology and catching up to technological developments,? Ingram told RT. ?
While very quick to react to breaches s of democracy in other nations, the West has been reluctant to openly criticize its allies in the Gulf region as the need to maintain the status quo.
?Western countries still want to see stability in the region and the continuance of the status quo, so this overrides any concerns that they may have. Yes, they have attempted to put some pressure on Bahrain, for instance, but overall they want to see the status quo maintained,? says Ingram.
Source: http://rt.com/news/qatar-online-media-crackdown-098/
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PST: Villa at top of Tottenham's wish list
Tottenham are already planning for next season.
And David Villa seems to be the man at the top of Andre Vilas-Boas? wishlist.
The Spanish star has just one year left on his contract at Barcelona, with the 31-year-old striker looking for a fresh challenge after a frustrating last few seasons at Barcelona.
A bad leg break and loss of form have hampered Villa?s appearances since the 2011-12 season, but he would be a steal at $15-18 million, as is rumored to be the price tag around his neck.
But do Spurs really need a striker? Oh yes.
For most of last season Gareth Bale was their one and only option for goals. He managed 21 in the league from a deep-lying position on the wing or in midfield.
Think how well Spurs could?ve done if they had a 15-20 goal striker to add to Bale?s dominance? That is scary. Only Everton from the EPL?s top seven scored less than Spurs? 66 goals last season.
AVB knows he?s not too far away from building a side that can compete with the top two. Spurs just need an extra spark up front if they?re going to get to that next level.
Can Villa provide that? Perhaps. He is a quality finisher, has won just about every trophy in the land and a change of scenery and new challenge could be the making of him. Here is a little visual reminder of what the former Valencia star can do. Enjoy.
If you look at Jermain Defoe and Emmanuel Adebayor this season, Tottenham?s two main strikers, they scored 16 league goals between them. If you are challenging for a top four spot, you should be expecting 16 goals from each of your main strikers.
That proved to be the difference for Spurs as they narrowly missed out on Champions League qualification to North London rivals Arsenal on the final day of the season.
Sorry for the painful reminder, Spurs fans.
So Villa could be the answer. If not, AVB knows he needs to strengthen going forward. But with Clint Dempsey injured for vast swathes of the 2012-13 season, maybe he can provide the answer to boost Tottenham?s goalscoring prowess?
Just throwing that out there. Regardless, it would be great to see Villa suit up in the EPL.
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Pets Of The Week: Can You Resist? ? CBS Detroit
Tiffany will be ready for adoption July 14 through Detroit Dog Rescue. (Photo: DDR)
DETROIT (CBS Detroit) Tiffany and Sapphire have a couple of things in common: One: They?re too cute for words.
And two: They started life in unfortunate circumstances.
Baby girls Sapphire and Tiffany were born after Detroit Dog Rescue received a call from a Detroit firefighter who noticed a dog in the front room of an abandoned home.
?After checking out the situation (which he stated was horrific) he noticed that she was pregnant,? said David Rudolph of DDR. ?We immediately took her to the vet for an exam and then she was placed in a foster home so she could have her little babies.?
And here they are. The pair were born on Tigers Opening Day and are ?doing great,? Rudolph said, adding the terrier mixes should be ready for adoption July 14th. If they?re the dogs for you, email dericsonpr@gmail.com to meet the puppies in person.
See Tiffany, Sapphire and the rest of our pets of the week HERE.
Source: http://detroit.cbslocal.com/2013/05/31/pets-of-the-week-can-you-resist/
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